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- From: jmoulder@its.mcw.edu (John Moulder)
- Newsgroups: sci.med.physics,sci.answers,news.answers
- Subject: Powerlines and Cancer FAQs (1 of 4)
- Supersedes: <jmoulder-281293173714@admin-one.radbio.mcw.edu>
- Followup-To: sci.med.physics
- Date: 25 Mar 1994 18:00:19 GMT
- Organization: Medical College of Wisconsin
- Lines: 545
- Approved: new-answers-request@MIT.edu
- Distribution: world
- Expires: 30 April 1994 00:00:00 GMT
- Message-ID: <jmoulder-250394115747@admin-one.radbio.mcw.edu>
- Reply-To: jmoulder@its.mcw.edu (John Moulder)
- NNTP-Posting-Host: admin-one.radbio.mcw.edu
- Summary: Q&As on the connection between powerlines, electrical
- occupations and cancer. Discussion of the biophysics of
- interactions with EM sources, summaries of the laboratory
- and human studies, information on standards, and references.
- Keywords: powerlines, magnetic fields, cancer, EMF, non-ionizing
- radiation, FAQ
- Xref: bloom-beacon.mit.edu sci.med.physics:1292 sci.answers:1011 news.answers:16847
-
- Archive-name: powerlines-cancer-FAQ/part1
- Last-modified: 1994/3/25
- Version: 2.4
-
- FAQs on Power-Frequency Fields and Cancer (part 1 of 4)
-
- Current version available by anonymous FTP from "rtfm.mit.edu" Directory:
- /pub/usenet-by-group/news.answers/powerlines-cancer-FAQ
- Files: part1, part2, part3, etc. . . .
-
- Revision notes:
- v2.4 (23-Mar-94): Expanded to four parts. Added table of contents.
- Expanded and annotated bibliography. Modified and expanded non-ionizing
- bioeffects sections. Expanded discussion of field reduction techniques.
- Added sections on measurement techniques. Expanded section on laboratory
- studies and broke into multiple parts. Added short section and references
- on reproductive toxicity studies.
-
- Table of Contents:
- Part 1
- 1) Why is there a concern about powerlines and cancer?
- 2) What is the difference between the electromagnetic (EM) energy
- associated with power lines and other forms of EM energy such as microwaves
- or x-rays?
- 3) Why do different types of EM sources produce different biological
- effects?
- 4) What is difference between EM radiation and EM fields?
- 5) Do power lines produce EM radiation?
- 6) How do ionizing EM sources cause biological effects?
- 7) How do RF, MW, visible light, and IR light sources cause biological
- effects?
- 8) How do the power-frequency EM fields cause biological effects?
- 9) Do non-ionizing EM sources cause non-thermal as well as thermal effects?
- 10) What sort of power-frequency magnetic fields are common in residences
- and workplaces?
- 11) Can power-frequency fields in homes and workplaces be reduced?
- 12) What is known about the relationship between powerline corridors and
- cancer rates?
- 13) How big is the "cancer risk" associated with living next to a
- powerline?
- 14) How close do you have to be to a power line to be considered exposed to
- power-frequency magnetic fields?
- 15) What is known about the relationship between "electrical occupations"
- and cancer rates?
-
- Part 2
- 16) What do laboratory studies tell us about power-frequency fields and
- cancer?
- 16A) Are power-frequency fields genotoxic?
- 16B) Are power-frequency magnetic fields cancer promoters?
- 16C) Do power-frequency magnetic fields enhance the effects of other
- genotoxic agents?
- 17) How do laboratory studies of the effects of power-frequency fields on
- cell growth, immune function, and melatonin relate to the question of
- cancer risk?
- 18) Do power-frequency fields show any effects at all in laboratory
- studies?
- 19) What about the new "Swedish" study showing a link between power lines
- and cancer?
- 20) What criteria do scientists use to evaluate all the confusing and
- contradictory laboratory and epidemiological studies of power-frequency
- magnetic fields and cancer?
- 20A) Criterion One: How strong is the association between exposure
- to power-frequency fields and the risk of cancer?
- 20B) Criterion Two: How consistent are the studies of associations
- between exposure to power-frequency fields and the risk of cancer?
- 20C) Criterion Three: Is there a dose-response relationship between
- exposure to power-frequency fields and the risk of cancer?
- 20D) Criterion Four: Is there laboratory evidence for an association
- between exposure to power-frequency fields and the risk of cancer?
- 20E) Criterion Five: Are there plausible biological mechanisms that
- suggest an association between exposure to power-frequency fields
- and the risk of cancer?
- 21) If exposure to power-frequency magnetic fields does not explain the
- residential and occupations studies which show increased cancer incidence,
- what other factors could?
- 21A) Could problems with dose assessment affect the validity of the
- epidemiological studies of power lines and cancer?
- 21B) Are there other cancer risk factors that could be causing a
- false association between exposure to power-frequency fields and
- cancer?
- 21C) Could the epidemiological studies of power lines and cancer be
- biased by the methods used to select control groups?
- 21D) Could analysis of the epidemiological studies of power lines
- and cancer be skewed by publication bias?
- 22) What is the strongest evidence for a connection between power-frequency
- fields and cancer?
- 23) What is the strongest evidence against a connection between
- power-frequency fields and cancer?
- 24) What studies are needed to resolve the cancer-EMF issue?
- 25) Is there any evidence that power-frequency fields could cause health
- effects other than cancer.
-
- Part 3
- 26) What are some good overview articles?
- 27) Are there exposure guidelines for power-frequency fields?
- 28) What effect do powerlines have on property values?
- 29) What equipment do you need to measure power-frequency magnetic fields?
- 30) How are power-frequency magnetic fields measured?
-
- Annotated Bibliography
- A) Recent Reviews of the Biological and Health Effects of Power-Frequency
- Fields
- B) Reviews of the Epidemiology of Exposure to Power-Frequency Fields
- C) Epidemiology of Residential Exposure to Power-Frequency Fields
- D) Epidemiology of Occupational Exposure to Power-Frequency Fields
- E) Human Studies Related to Power-Frequency Exposure and Cancer
- F) Biophysics and Dosimetry of Power-Frequency Fields
-
- Part 4
- G) Laboratory Studies of Power-Frequency Fields and Cancer
- H) Laboratory Studies Indirectly Related to Power-Frequency Fields and
- Cancer
- J) Laboratory Studies of Power-Frequency Fields and Reproductive Toxicity
- K) Reviews of Laboratory Studies of Power-Frequency Fields
- L) Miscellaneous Studies
- M) Regulations and Standards for Ionizing and Non-ionizing EM Sources.
-
- -----
-
- 1) Why is there a concern about powerlines and cancer?
-
- Most of the concern about power lines and cancer stems from epidemiological
- studies of people living near powerlines, and epidemiological studies of
- people working in "electrical occupations". Some of these epidemiological
- studies appear to show a relationship between exposure to power-frequency
- magnetic fields and the incidence of cancer. Laboratory studies have shown
- little evidence of a link between power-frequency fields and cancer.
-
- 2) What is the difference between the electromagnetic (EM) energy
- associated with power lines and other forms of EM energy such as microwaves
- or x-rays?
-
- X-rays, ultraviolet (UV) light, visible light, infrared light (IR),
- microwaves (MW), radiowaves (RF), and electromagnetic fields from
- electrical power systems are all parts of the EM spectrum. The parts of
- the EM spectrum are characterized by their frequency or wavelength. The
- frequency and wavelength are related, and as the frequency rises the
- wavelength gets shorter. The frequency is the rate at which the EM field
- changes direction and is usually given in Hertz (Hz), where one Hz is one
- cycle per second.
-
- Power-frequency fields in the US vary 60 times per second, so they are 60
- Hz fields, and have a wavelength of 3000 miles (5000 km). Power in most of
- the rest of the world is at 50 Hz. The power-frequency fields are often
- referred to as extremely low frequencies or ELF. Broadcast AM radio has a
- frequency of around one million Hz and a wavelength of around 1000 ft (300
- m). Microwave ovens have a frequency of about 2.5 billion Hz, and a
- wavelength of about 5 inches (12 cm). X-rays and UV light have frequencies
- of millions of billions of Hz, and wavelengths of less than a thousandth of
- an inch (10 nm or less).
-
- 3) Why do different types of EM sources produce different biological
- effects?
-
- The interaction of biological material with an EM source depends on the
- frequency of the source. We usually talk about the EM spectrum as though
- it produced waves of energy. This is not strictly correct, because
- sometimes EM energy acts like particles rather than waves; this is
- particularly true at high frequencies. This double nature of the EM
- spectrum is referred to as "wave-particle duality". The particle nature of
- EM energy is important because it is the energy per particle (or photons,
- as these particles are called) that determines what biological effects EM
- energy will have.
-
- At the very high frequencies characteristic of UV light and X-rays, EM
- particles (photons) have sufficient energy to break chemical bonds. This
- breaking of bonds is termed ionization, and this portion of the EM spectrum
- is termed ionizing radiation. The well-known biological effects of X-rays
- are associated with the ionization of molecules. At lower frequencies,
- such as those characteristic of visible light, RF, and MW, the photons do
- not carry enough energy to break chemical bonds. This portion of the EM
- spectrum is termed the non-ionizing portion. At RF and MW frequencies the
- energy of a photon is very much (by a factor of thousands or more) below
- those needed to disrupt chemical bonds. For this reason, there is no
- analogy between the biological effects of ionizing and nonionizing EM
- energy.
-
- Non-ionizing EM sources can still produce biological effects. One
- mechanism is by inducing electrical currents in tissues, which cause
- heating by moving ions and water molecules through the viscous medium in
- which they exist. The efficiency with which an EM source can induce
- electrical currents, and thus produce heating, depends on the frequency of
- the source, and the size and orientation of the object being heated. At
- frequencies below that used for broadcast AM radio, EM sources couple
- poorly with the bodies of humans and animals, and thus are very inefficient
- at inducing electrical currents and causing heating.
-
- Thus in terms of potential biological effects the EM spectrum can be
- divided into the three portions:
- 1) The ionizing portion, where direct chemical damage can occur (X-rays,
- hard UV).
- 2) The portion of the non-ionizing spectrum in which the wavelength is
- smaller than that of the body, where heating can occur (visible light, IR,
- MW and RF).
- 3) The portion of the non-ionizing spectrum in which the wavelength is much
- larger than that of the body, where heating seldom occurs (power
- frequencies).
-
- 4) What is difference between EM radiation and EM fields?
-
- When dealing with fields from an EM source it is customary to distinguish
- between fields (which do not transmit energy to infinity from the source)
- and radiation (which does). In general, EM sources produce both radiant
- energy (radiation) and non-radiant energy (fields). Radiated energy exists
- apart from its source, travels away from the source, and continues to exist
- even if the source is turned off. Non-radiant energy is not projected away
- into space, and it ceases to exist when the energy source is turned off.
- When a person or object is more than several wavelengths from an EM source,
- a condition called far-field, the radiation component of the EM source
- dominates. When a person or object is less than one wavelength from an EM
- source, a condition called near-field, the field effect dominates, and the
- electrical and magnetic components are unrelated.
-
- For ionizing frequencies where the wavelengths are less than a thousandth
- of an inch (less than 10 nm), human exposure is entirely in the far-field,
- and only the radiation from the EM source is relevant to health effects.
- For MW and RF, where the wavelengths are in inches to a few thousand feet
- (a few cm to a km), human exposure can be in both the near- and far-field,
- so that both field and radiation effects can be relevant. For
- power-frequency fields, where the wavelength is thousands of miles
- (thousands of km), human exposure is always in the near-field, and only the
- field component is relevant to possible health effects.
-
- 5) Do power lines produce EM radiation?
-
- The fields associated with transmission lines are purely near-field. While
- the lines theoretically might radiate some energy the efficiency of this is
- so low that this effect can for all practical purposes be ignored. To be
- an effective radiation source an antenna must have a length comparable to
- its wavelength. Power-frequency sources are clearly too short compared to
- their wavelength (3000 miles, 5000 km) to be effective radiation sources.
-
- This is not to say that there is no loss of power during transmission.
- There are many sources of loss in transmission lines that have nothing to
- do with "radiation" (in the sense as it is used in EM theory). Loss of
- energy is a result of resistive heating, not "radiation". This is in sharp
- contrast to RF antennas, which "lose" energy to space by radiation.
- Likewise, there are many ways of transmitting energy from point A to point
- B that do not involve radiation. Electrical circuits do it all the time.
-
- The only "practical" exception to the statement that power-frequency fields
- do not radiate is the use of ELF antennas to broadcast to submerged
- submarines. The US Navy runs a power-frequency antenna in Northern
- Wisconsin and the Upper Peninsula of Michigan. To overcome the inherent
- inefficiency of the frequency, the antenna is several hundred kilometers in
- length.
-
- 6) How do ionizing EM sources cause biological effects?
-
- Ionizing EM radiation carries sufficient energy per photon to break
- chemical bonds. In particular, ionizing radiation is capable of breaking
- bonds in the genetic material of the cell, the DNA. Severe damage to DNA
- can kill cells, resulting in tissue damage or death. Lesser damage to DNA
- can result in permanent changes in the cells which may lead to cancer. If
- these changes occur in reproductive cells, they can lead to inherited
- changes, a phenomena called mutation. All of the known hazards from
- exposure to the ionizing portion of the EM spectrum are the result of the
- breaking of chemical bonds in DNA. For frequencies below that of UV light,
- DNA damage does not occur because the photons do not have enough energy to
- break chemical bonds. Well-accepted safety standards exist to prevent
- significant damage to the genetic material of persons exposed to ionizing
- EM radiation [M3].
-
- 7) How do RF, MW, visible light, and IR light sources cause biological
- effects?
-
- A principal mechanism by which RF, MW, visible light, and IR light sources
- cause biological effects is by heating (thermal effects). This heating can
- kill cells. If enough cells are killed, burns and other forms of
- long-term, and possibly permanent tissue damage can occur. Cells which are
- not killed by heating gradually return to normal after the heating ceases;
- permanent non-lethal cellular damage is not known to occur. At the
- whole-animal level, tissue injury and other thermally-induced effects can
- be expected when the amount of power absorbed by the animal is similar to
- or exceeds the amount of heat generated by normal body processes. Some of
- these thermal effects are very subtle, and do not represent biological
- hazards.
-
- It is possible to produce thermal effects even with very low levels of
- absorbed power. One example is the "microwave hearing" phenomenon; these
- are auditory sensations that a person experiences when his head is exposed
- to pulsed microwaves such as those produced by radar. The ╥microwave
- hearing╙ effects is a thermal effect, but it can be observed at very low
- average power levels.
-
- Since thermal effects are produced by heat, not by the electric or magnetic
- fields directly, they can be produced by fields at many different
- frequencies. Well-accepted safety standards exist to prevent significant
- thermal damage to persons exposed to MW and RFs [M2] and also for persons
- exposed to lasers, IR and UV light [M4].
-
- 8) How do the power-frequency EM fields cause biological effects?
-
- The electrical and magnetic fields associated with power-frequency fields
- cannot break bonds because the energy per photon is too low. The magnetic
- field intensities to which people are exposed in residential settings and
- in the vast majority of occupational settings cannot cause heating because
- the induced electrical currents are too low. Thus the known mechanisms
- through which ionizing radiation, MWs and RFs effect biological material
- have no relevance for power-frequency fields.
-
- The electrical fields associated with the power-frequency fields exist
- whenever voltage is present, and regardless of whether current is flowing.
- These electrical fields have very little ability to penetrate buildings or
- even skin. The magnetic fields associated with power-frequency fields
- exist only when current is flowing. These magnetic fields are difficult to
- shield, and easily penetrate buildings and people. Because power-frequency
- electrical fields do not penetrate, any biological effects from routine
- exposure to power-frequency fields must be due to the magnetic component of
- the field.
-
- Exposure of people to power-frequency magnetic fields results in the
- induction of electrical currents in the body. If these currents are
- sufficiently intense, they can cause heating, nerve excitation and other
- effects [F4,K1]. At power frequencies, the body is poorly coupled to
- external fields, and the induced currents are usually too small to produce
- obvious effects. Shocks, and other obvious effects usually require that
- the body actually touch a conductive objects, allowing current to pass
- directly into the body.
-
- It requires a power-frequency magnetic field in excess of 5 Gauss (500
- microT, see Question 10 for typical exposures) to induce electrical
- currents of a magnitude similar to those that occur naturally in the body.
- Well-accepted safety standards exist to protect persons from exposure to
- power-frequency fields that would induce such currents (Question 27).
-
- 9) Do non-ionizing EM sources cause non-thermal as well as thermal effects?
-
- One distinction that is often made in discussions of the biological effects
- of non-ionizing EM sources is between "nonthermal" and "thermal" effects.
- This refers to the mechanism for the effect, non-thermal effects being a
- result of a direct interaction between the field and the organism, and
- thermal effects being a result of heating. Microwave burns are an obvious
- thermal effect, and electrical shocks are an obvious nonthermal effect.
- There are many reported biological effects (some of which have not been
- reproduced) whose mechanisms are totally unknown, and one should be very
- careful about drawing the distinction between "thermal" and "nonthermal"
- mechanisms for such effects.
-
- 10) What sort of power-frequency magnetic fields are common in residences
- and workplaces?
-
- In the US magnetic fields are commonly measured in Gauss (G) or milliGauss
- (mG), where 1,000 mG = 1G. In the rest of the world, they are measured in
- Tesla (T), were 10,000 G equals 1 T (1 G = 100 microT; 1 microT = 10 mG).
- Power-frequency fields are measured with a calibrated gauss meter
- (Questions 29 & 30).
-
- Within the right-of-way (ROW) of a high-voltage (115-765 kV,
- 115,000-765,000 volt) transmission line, fields can approach 100 mG (0.1 G,
- 10 microT). At the edge of a high-voltage transmission ROW, the field will
- be 1-10 mG (0.1-1.0 microT). Ten meters from a 12 kV (12,000 volt)
- distribution line fields will be 2-10 mG (0.2-1.0 microT). Actual fields
- depend on voltage, design and current.
-
- Fields within residences vary from over 1000 mG (100 microT) a few inches
- (cm) from certain appliances to less than 0.2 mG (0.02 microT) in the
- center of some rooms. Appliances that have the highest fields are those
- with high currents (e.g., toasters, electric blankets) or high-speed
- electric motors (e.g., vacuum cleaners, electric clocks, blenders, power
- tools). Appliance fields decrease very rapidly with distance. See
- Theriault [F3] for further details.
-
- Occupational exposures in excess of 1000 mG (100 microT) have been reported
- (e.g., in arc welders and electrical cable splicers). In "electrical"
- occupations typical mean exposures range from 5 to 40 mG (0.5 to 4 microT).
- See Theriault [F3] for further details.
-
- 11) Can power-frequency fields in homes and workplaces be reduced?
-
- There are engineering techniques that can be used to decrease the magnetic
- fields produced by power lines, substations, transformers and even
- household wiring and appliances. Once the fields are produced, however,
- shielding is very difficult. Small area can be shielded by the use of Mu
- metal, a nickel-iron-copper alloy with "high magnetic permeability and low
- hysteresis losses". Mu metal shields are very expensive, and limited to
- small volumes.
-
- Increasing the height of towers, and thus the height of the conductors
- above the ground, will reduce the field intensity at the edge of the ROW.
- The size, spacing and configuration of conductors can be modified to reduce
- magnetic fields, but this approach is limited by electrical safety
- considerations. Placing multiple circuits on the same set of towers can
- also lower the field intensity at the edge of the ROW, although it
- generally requires higher towers. Replacing lower voltage lines with
- higher voltage ones can also lower the magnetic fields.
-
- Burying transmission lines greatly reduces their magnetic fields. The
- reduction occurs because the underground lines use rubber, plastic or oil
- for insulation rather than air. This allows the conductors to be placed
- much closer together and allows greater phase cancellation. However,
- placing high voltage lines underground is very expensive, adding costs that
- are measured in hundreds of thousands of US dollars per mile.
-
- 12) What is known about the relationship between powerline corridors and
- cancer rates?
-
- Some studies have shown that children living near certain types of
- powerlines (high current distribution lines and transmission lines) have
- higher than average rates of leukemia [C1,C6,C10,C17], brain cancers
- [C1,C6] and/or overall cancer [C5,C15]. The correlations are not strong,
- and none of the studies have shown dose-response relationships. When
- power-frequency fields are actually measured, the correlation vanishes
- [C6,C10,C17]. Several other studies have shown no correlations between
- residence near power lines and risks of childhood leukemia
- [C3,C5,C7,C8,C9,C14,C15], childhood brain cancer [C5,C8,C14,C15,C17], or
- overall childhood cancer [C14,C17]. With one exception [C2] all studies of
- correlations between adult cancer and residence near power lines have been
- negative [C4,C8,C9,C11,C12,C16].
-
- 13) How big is the "cancer risk" associated with living next to a
- powerline?
-
- The excess cancer found in epidemiological studies is usually quantified in
- a number called the relative risk (RR). This is the risk of an "exposed"
- person getting cancer divided by the risk of an "unexposed" person getting
- cancer. Since no one is unexposed to power-frequency fields, the
- comparison is actually "high exposure" versus "low exposure". A RR of 1.0
- means no effect, a RR of less the 1.0 means a decreased risk in exposed
- groups, and a RR of greater than one means an increased risk in exposed
- groups. Relative risks are generally given with 95% confidence intervals.
- These 95% confidence intervals are almost never adjusted for multiple
- comparisons even when multiple types of cancer and multiple indices of
- exposure are studied (see Olsen et al, [C15], Fig. 2 for an example of a
- multiple-comparison adjustment).
-
- An overview of the epidemiology requires that studies be combined using a
- technique known as "meta-analysis". Meta-analysis is not easy to do, since
- the epidemiological studies of residential exposure use a wide variety of
- methods for assessing "exposure". Meta-analysis also gets out-of-date
- rapidly in this field. The following RRs (called summary RRs in
- meta-analysis) for the residential exposure studies are adapted from
- Hutchison [B4] and Doll et al [B5] by inclusion of the new European studies
- (Question 19). The confidence intervals should be viewed as measures of
- the diversity of the data, rather than as strict tests of the statistical
- significance of the data.
- childhood leukemia: 1.5 (0.8-3.0) 8 studies
- childhood brain cancer: 1.9 (0.9-3.0) 6 studies
- childhood lymphoma: 2.5 (0.3-40) 2 studies
- all childhood cancer: 1.5 (0.9-2.5) 5 studies
- adult leukemia: 1.1 (0.8-1.6) 3 studies
- adult brain cancer: 0.7 (0.4-1.3) 1 study
- all adult cancer: 1.1 (0.9-1.3) 3 studies
-
- As a base-line for comparison, the age-adjusted cancer incidence rate for
- adults in the United States is 3 per 1,000 per year for all cancer (that
- is, 0.3% of the population gets cancer in a given year),and 1 per 10,000
- per year for leukemia [E6].
-
- 14) How close do you have to be to a power line to be considered exposed to
- power-frequency magnetic fields?
-
- The epidemiological studies that show a relationship between cancer and
- powerlines do not provide any consistent guidance as to what distance or
- exposure level is associated with increased cancer incidence. The studies
- have used a wide variety of techniques to measure exposure, and they differ
- in the type of lines that are studied. The US studies have been based
- predominantly on neighborhood distribution lines, whereas the European
- studies have been based strictly on high-voltage transmission lines and/or
- transformers.
-
- Field measurements: Several studies have measured power-frequency fields in
- the residences [C6,C7,C10,C12,C17]. Both one-time (spot), peak, and
- 24-hour average measurement have been made; none of the studies using
- measured fields have shown a relationship between exposure and cancer.
-
- Proximity to lines: Several studies have used the distance from the power
- line corridor to the residence as a measure of power-frequency fields
- [C4,C5,C8,C9,C8,C9,C11,C12,C17]. When something we can measure (distance
- to the line), is used as an index of what we really want to measure (the
- magnetic field), it is called a surrogate (or proxy) measure. With two
- exception [C5,C17], studies that have used distance from power lines as a
- surrogate measure of exposure have shown no significant relationship
- between proximity to lines and the incidence of cancer. The major
- exception is a childhood leukemia study [C17] that showed a significant
- increase in leukemia incidence for residence within 50 m (150 ft) of
- high-voltage transmission lines. This same study [C12,C17] showed no
- elevation of child leukemia risks at 51-100 m (150-300 ft), and no increase
- in childhood brain cancer, overall childhood cancer, or any types of adult
- cancer at any distance.
-
- Wire Codes: The original US powerline studies used a combination of the
- type of wiring (distribution vs transmission, number and thickness of
- wires) and the distance from the wiring to the residence as a surrogate
- measure of exposure [C1,C2,C3,C6,C7,C10]. This technique is known as
- "wirecoding". Three studies using wirecodes [C1,C6,C10] have shown a
- relationship between childhood cancer and "high-current configuration"
- wirecodes. Two of these studies [C6,C10] failed to show a significant
- relationship between exposure and cancer when actual measurements were
- made. Wirecodes are stable over time [F5] and correlate with measured
- fields, although the correlation is not very good [F1]. The wirecode
- scheme was developed for the U.S., and does not appear to be readily
- applicable elsewhere.
-
- Calculated Historic Fields: The recent European studies have used utility
- records and maps to calculate what fields would have been produced by power
- lines in the past [C12,C14,C15,C17]. Typically, the calculated field at
- the time of diagnosis or the average field for a number of years prior to
- diagnosis are used as a measure of exposure (Question 19). These
- calculated exposures explicitly exclude contributions from other sources
- such as distribution lines, household wiring, or appliances. When the
- field calculations are done for contemporary measured fields they correlate
- reasonably well [C17]. Of course, there is no way to check the accuracy of
- the calculated historic fields.
-
- 15) What is known about the relationship between "electrical occupations"
- and cancer rates?
-
- Several studies have shown that people who work in electrical occupations
- have higher than average cancer rates. The original studies [D1,D2 were
- only of leukemia. Some later studies also implicated brain, lymphoma
- and/or breast cancer [B1,B2,B3,B4,B5]. Most of the cautions listed for the
- residential studies apply here also: many negative studies, weak
- correlations, no dose-response relationships. Additionally, these studies
- are mostly based on job titles, not on measured exposures.
-
- Meta-analysis of the occupational studies is even more difficult than the
- residential studies. First, a variety of epidemiological techniques are
- used, and studies using different techniques should not really be combined.
- Second, a wide range of definitions of "electrical occupations" are used,
- and very few studies actually measured exposure. The following RRs
- (Question 13) for the occupational exposure studies are adapted from
- Hutchison [B4] and Davis et al [A2]. Again, the confidence intervals
- should be viewed as measures of diversity rather than as tests of the
- statistical significance.
- leukemia: 1.15 (1.0-1.3) 28 studies
- brain: 1.15 (1.0-1.4) 19 studies
- lymphoma: 1.20 (0.9-1.5) 6 studies
- all cancer: 1.00 (0.9-1.1) 8 studies
-
- The above relative risks do not take into account more recent studies. Two
- recent European studies [D7,D9] have found excess leukemia in electrical
- occupations, but no excess of other types of cancer (Question 19 for
- details).
-
- Two other new occupational exposure studies [D4,D5] shows small but
- statistically significant increases in leukemia, but others [D3,D6,D8] do
- not. None of the new studies of electrical occupations show significant
- elevation of any types of cancer other than leukemia (specifically brain
- cancer or lymphoma)[D5,D7,D8,D9]. Adding these seven new studies raises
- the summary RR for leukemia slightly, and lowers the summary RRs for brain
- cancer and lymphomas to essentially one.
-
- End: powerlines-cancer-FAQ/part1
-